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Therapeutic inhibitor for EBV-associated tumor with tailor responsive optical imaging

Summary

provides method of treating and imaging EBV-associated cancers.

Technology Benefits

Treating and imaging EBV-associated cancers

Technology Application

detection diagnosis

Detailed Technology Description

This invention provides a nucleus-permeable small-molecule inhibitor, L2P4 (where L2 is 4-(4-(Diethylamino)styryl)-N-carboxymethylpyridinium chloride and P4 is an amino acid sequence comprising CAhxYFMVFGGRrRK and they were coupled through amide bond) and synthesis thereof, which effectively targets the dimerization interface of EBNA1, a critical process for the growth of EBVs and the associated tumors. The present invention also provides method of treating and imaging EBV-associated cancers.

Type of Cooperation

Licensing

Countries

Application Date

24/04/2017 00:00:00

Application No.

15/495,971

Patent Information

A61K/51/00

Others

CN, TW, EP

Country/Region

Hong Kong

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