Therapeutic inhibitor for EBV-associated tumor with tailor responsive optical imaging
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- 总结
- provides method of treating and imaging EBV-associated cancers.
- 技术优势
- Treating and imaging EBV-associated cancers
- 技术应用
- detection diagnosis
- 详细技术说明
- This invention provides a nucleus-permeable small-molecule inhibitor, L2P4 (where L2 is 4-(4-(Diethylamino)styryl)-N-carboxymethylpyridinium chloride and P4 is an amino acid sequence comprising CAhxYFMVFGGRrRK and they were coupled through amide bond) and synthesis thereof, which effectively targets the dimerization interface of EBNA1, a critical process for the growth of EBVs and the associated tumors. The present invention also provides method of treating and imaging EBV-associated cancers.
- 合作类型
- Licensing
- 国家
- US
- 申请日期
- 24/04/2017 00:00:00
- 申请号码
- 15/495,971
- 专利信息
- A61K/51/00
- 其他
- CN, TW, EP
- 国家/地区
- 香港
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