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Therapeutic inhibitor for EBV-associated tumor with tailor responsive optical imaging

       
總結
provides method of treating and imaging EBV-associated cancers.
技術優勢
Treating and imaging EBV-associated cancers
技術應用
detection diagnosis
詳細技術說明
This invention provides a nucleus-permeable small-molecule inhibitor, L2P4 (where L2 is 4-(4-(Diethylamino)styryl)-N-carboxymethylpyridinium chloride and P4 is an amino acid sequence comprising CAhxYFMVFGGRrRK and they were coupled through amide bond) and synthesis thereof, which effectively targets the dimerization interface of EBNA1, a critical process for the growth of EBVs and the associated tumors. The present invention also provides method of treating and imaging EBV-associated cancers.
合作類型
Licensing
國家
US
申請日期
24/04/2017 00:00:00
申請號碼
15/495,971
專利信息
A61K/51/00
其他
CN, TW, EP
國家/地區
香港

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