本发明提供一种利用多肽及其衍生物阻断肿瘤细胞增殖 的方法,其中多肽的核酸序 列 来自多种肿瘤细胞中高表达 TBX2 和 TBX3 的 cDNA 片段。所述的多肽 TAP21 含有 83 个氨基酸,分子量约为9kDa 。本发明还提供一种利用表达载体在大肠杆菌中表达并且纯化多肽的方法。与现有的抗癌药一个显著不同点在于,该多 肽由极强的靶性,对正常德 组 织和细胞无毒副作用。该多肽以小分子多肽形式直接导入 肿瘤细胞,它能明显抑制肿 瘤 细胞增殖,降低癌基因的表达,促进肿瘤细胞迅速凋亡,是肿瘤治疗过程中的潜在药物。 This invention provides effective peptides.....
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The alignment behavior of the liquid crystal layer of a liquid crystal display (LCD) determines most of its optical properties. The alignment direction and pretilt angles are determined by the alignment layers in contact with the liquid crystal layer itself and cannot be varied. Some traditional way.....
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Embodiments Of The Invention Are Directed To Luminescent Gold(Iii) Compounds Contains A Bidentate Ligand With At Least One Strong [Sigma]-Donating Group, A Method Of Preparation Of These Compounds And The Use Of These Compounds In Organic Light Emitting Devices. The Gold(Iii) Compounds Have The Chem.....
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Display is a large and still continuously expanding market. Flat-panel display is the dominating segment in the industry which involves the use of active-matrix driving technology. In conventional active matrix displays, thin film transistors (TFTs) are formed by amorphous silicon (a-Si). However, i.....
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A new formulation of dehydrated lipid vesicles employs a vesicle preserver and permits the control of release and delivery of active pharmaceutical ingredients into the respiratory system for treatment in particular of asthma.
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