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Novel Formulation of Dehydrated Lipid Vesicles for Controlled Release of Active Pharmaceutical Ingredient via Inhalation (用於控制釋放藥物活性成分的新型脂質體氣霧劑)

Summary

A new formulation of dehydrated lipid vesicles employs a vesicle preserver and permits the control of release and delivery of active pharmaceutical ingredients into the respiratory system for treatment in particular of asthma.

Technology Benefits

Allow prolonged therapeutic period for one administration, Increased stability with reduced dose, Reduce systemic side effects, Reduce toxicity

Technology Application

Treat asthma and other conditions

Detailed Technology Description

A new formulation of dehydrated lipid vesicles employs a vesicle preserver and permits the control of release and delivery of active pharmaceutical ingredients into the respiratory system for treatment in particular of asthma. The typical formulation provides controlled release of the active pharmaceutical ingredient from 0% to 100% from 0 to 72 hours after inhalation, changes the systemic administration to topical administration, allows prolonged therapeutic period for one administration, increased stability, with reduced dose, reduced systemic side effects, reduced toxicity

Supplementary Information

Patent Number: US20090047336A1
Application Number: US2007840537A
Inventor: Yang, Zhijun | Huang, Wenhua | Wong, Chi Sun | Zhao, Zhongzhen
Priority Date: 17 Aug 2007
Priority Number: US20090047336A1
Application Date: 17 Aug 2007
Publication Date: 19 Feb 2009
IPC Current: A61K0031137 | A61K0009127 | A61K000914 | A61K004706 | A61P001100 | A61P001106
US Class: 424450 | 424489 | 514653 | 514772
Assignee Applicant: Hong Kong Baptist University
Title: NOVEL FORMULATION OF DEHYDRATED LIPID VESICLES FOR CONTROLLED RELEASE OF ACTIVE PHARMACEUTICAL INGREDIENT VIA INHALATION
Usefulness: NOVEL FORMULATION OF DEHYDRATED LIPID VESICLES FOR CONTROLLED RELEASE OF ACTIVE PHARMACEUTICAL INGREDIENT VIA INHALATION
Summary: The pharmaceutical lipid composition is useful for treating respiratory system diseases, preferably asthma by inhalation into a respiratory system (claimed).
Novelty: Composition useful for treating respiratory system diseases, preferably asthma by inhalation into respiratory system, comprises dehydrated lipid vesicles of vesicle preserver, lipid component and active ingredient e.g. albuterol

Industry

Biomedical

Sub Category

Medical Composition

Application Date

2008.08.15
2007.08.17

Application No.

200810210952
US 11/840,537

Others

Published

ID No.

A61/YZ/Nove/CN01

Country/Region

Hong Kong