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A subchondral defect is usually characterized by a structural breakdown of the articular cartilage and the bone underneath due to trauma or disease, leading to chronic disabilities. Treating such defects is an important medical target since in the adult patient, damaged cartilage cannot spontaneousl..... [更多]
The geometry of crystals, bones and other natural objects can appear random. But they possess characteristic patterns which help attain beneficial features, such as aesthetics or structural strength. It is possible to generate such patterns in 2D, using a sample pattern for reference. These methods ..... [更多]
Highlights:p53, the most important tumour suppressor protein in the cell, is a homotetrameric protein that has a pivotal role in the cellular anti cancer defense mechanism.p53 is active as a tetramer: the tetramer binds DNA much tighter than the monomer / dimer and is retained in the nucleus while t..... [更多]
About 15% of couples trying to conceive are facing difficulties.Female tubal factors are by far the largest group causing 25-35% of all infertility cases, thus 2/3 of all non conceiving couples will undergo an investigation that includes tubal imaging, 10% of whom will be candidates for tubal recana..... [更多]
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