Although early programs targeting MMPs (matrix metalloproteins) were largely unsuccessful due to adverse side effects, they remain a viable and highly desirable therapeutic target. The main obstacle in the attempts to target MMPs is the ability to selectively target individual family members. The pr.....
[更多]
A field deployable device for near real-time identification and quantitiatve measurement of genotoxins in water. The device contains a low cost disposable probe head which quickly and accurately alerts if genotoxins are present at dangerous levels. The probe consists of genetically modified bacteri.....
[更多]
A universal computational framework for identifying molecular pathways underlying cancer viability and resistance. Our approach is applied to mining large collections of cancer patients’ data and identifying classes of genetic interactions termed synthetic lethality (SL). Synthetic lethality - The d.....
[更多]
