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A universal computational framework for identifying molecular pathways underlying cancer viability and resistance. Our approach is applied to mining large collections of cancer patients’ data and identifying classes of genetic interactions termed synthetic lethality (SL). Synthetic lethality - The d..... [更多]
Particle analyzers utilize particle 'focusing' by establishing high particle concentrations within a thin stream of gas. Most specimens for analysis, like gunpowder residue in ambient air, do not show these properties. Aerodynamic lens arrays which consist of many tubes which reshape the particle fl..... [更多]
A subchondral defect is usually characterized by a structural breakdown of the articular cartilage and the bone underneath due to trauma or disease, leading to chronic disabilities. Treating such defects is an important medical target since in the adult patient, damaged cartilage cannot spontaneousl..... [更多]
Background:Stirling cycle-based cryocoolers employ mechanical compressors activated by inductive electrical motors producing an oscillating pressure in a gas. The main disadvantage of these conventional compressors is their limited lifetime, caused by mechanical friction and wear. Wear products degr..... [更多]
A test method based on a genetic polymorphism in the Haptoglobin gene identifies those individuals with Diabetes who are at high risk for developing heart, eye and kidney disease and who benefit from specific drug treatments, has been validated in multiple clinical trials worldwide. Diabetes is one..... [更多]
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