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Additional material on the technology can be supplied upon request [更多]
BBS is a monoclonal antibody that binds specifically and blocks beta-secretase (BACE1) cleavage site on its substrate, APP. BBS inhibits Ab production, a hall-mark of AD and other neurodegenerative diseases such as ALS.The mechanism of action of BBS is based on binding of the antibody at the cell s..... [更多]
Female mice are fed with diets rich in specific f.a. (saturated or unsaturated) during pregnancy and/or lactation. The offspring is raised on a regular diet or on a fat rich diet, and develops obesity, fatty liver, and insulin resistance, depending on the diet received in utero. The model allows stu..... [更多]
Novel approach for the treatment of Cytomegalovirus (CMV) infection. The technology addresses unmet medical need in the field of CMV management. The use of currently available anti-CMV drugs is limited due to toxicity, low oral bioavailability and drug resistance.We have a pre- clinical proof of co..... [更多]
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