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The Technology:Calcitriol (1,25-dihydroxyvitamin D3), the main hormonally active metabolite of vitamin D was found, in vitro, together with some of its synthetic analogs to have the potential to reduce the damage inflicted to normal tissue by accepted anti-cancer therapy. Calcitriol was found to aff..... [更多]
The Technology:Calcitriol (1,25-dihydroxyvitamin D3), the main hormonally active metabolite of vitamin D was found, in vitro, together with some of its synthetic analogs to have the potential to reduce the damage inflicted to normal tissue by accepted anti-cancer therapy. Calcitriol was found to aff..... [更多]
Highlights:p53, the most important tumour suppressor protein in the cell, is a homotetrameric protein that has a pivotal role in the cellular anti cancer defense mechanism.p53 is active as a tetramer: the tetramer binds DNA much tighter than the monomer / dimer and is retained in the nucleus while t..... [更多]
Highlights:p53, the most important tumour suppressor protein in the cell, is a homotetrameric protein that has a pivotal role in the cellular anti cancer defense mechanism.p53 is active as a tetramer: the tetramer binds DNA much tighter than the monomer / dimer and is retained in the nucleus while t..... [更多]
Prostate cancer (CaP), an adenocarcinoma of the prostate, is the most common cancer in American males over the age of 55 and the second cause of cancer-related mortality. The current diagnosis of prostate cancer is based on the measurements of serum prostate-specific antigen (PSA) levels. Unfortunat..... [更多]
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