This invention provides an isolated DNA comprising the sequence which codes for a mutated collagen X or a portion thereof wherein the expression of said DNA regulates bone growth. This invention provides a polypeptide encoded by the isolated DNA comprising the sequence which codes for a mutated coll.....
[Detail]
The present invention provides the use of analogues and derivatives of dinucleoside polyphosphates with formula (I) or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for use in one or more of: the treatment of ischemia, inducing ischemic tolerance, modulating cerebral.....
[Detail]
Methods And Compositions For Identifying And Treating Obesity And Obesity-Induced Metabolic Disorders Are Provided. One Aspect Provides A Method For The Evaluation Of Risk And Progression Of Glucose Tolerance, Insulin Resistance And Type 2 Diabetes In Mammalian Subjects. The Method Includes Measurin.....
[Detail]
This invention provides a method for treating or preventing human atrial arrhythmia (fibrillation) using the leading flavone compound acacetin, and its derivatives and analogues that inhibit the ultra-rapidly-activating delayed rectifier potassium current (IKur or IKsus), transient outward potassium.....
[Detail]
This invention provides a method for treating or preventing human atrial arrhythmia (fibrillation) using the leading flavone compound acacetin, and its derivatives and analogues that inhibit the ultra-rapidly-activating delayed rectifier potassium current (IKur or IKsus), transient outward potassium.....
[Detail]
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