The present invention identifies and describes several genes that may account for at least 14% of young onset diabetes in Chinese. These include novel mutations in the glucokinase and hepatocyte nuclear factor-1 genes, as well as known mutations in the amylin gene and mitochondrial DNA. This cat.....
[Detail]
The present invention identifies and describes a combination of genetic markers that are associated with increased risk for diabetic nephropathy, either independently or through interactions with obesity, blood pressure and lipid controls. These polymorphisms include the lipoprotein lipase (Ser447T.....
[Detail]
The present invention provides an efficient gene delivery system using Adeno-Associated Viral (AAV) vector in gene therapy. Furthermore, the invention provides a combined AAV and Adenovirus (Adv) cocktail gene delivery system which is even more efficient in in vivo gene delivery and expression witho.....
[Detail]
