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This technology serves as a prototype for rapid and inexpensive detection of specific HLA genotype using HLA‐B*1502 as an example. The rapid test for B*1502 allele by simple set‐up and at low costs has far reaching pharmacogenetic implications in health care quality and resource allocation. It has ..... [Detail]
The present invention provides a new method of using femtosecond laser at the wavelength of 1550nm to briefly illuminate mammalian cells in order to perforate their plasma membrane and to transfect foreign DNA into the mammalian cells for protein expression. This system allows investigators and use..... [Detail]
The invention provides an effective and pragmatic means for controlled production of polymer-stabilized drug nanoparticles with the desired particle size and surface properties for specific biological and pharmaceutical applications. At present there are no available technologies or approaches that ..... [Detail]
SARS coronavirus can cause acute severe respiratory syndrome in humans and some animal model systems such as monkeys. The mortality rate can reach as high as 50% in people older than 65 of age. Recent technology in creating small interferening RNA can be used to inhibit viral gene expression and t..... [Detail]
Osteoporosis, a silent disease, is a skeletal disorder characterized by compromised bone strength predisposing to an increased risk of fractures. The global burden of osteoporosis is significant nowadays – over 200 million people worldwide and approximately 30% of all postmenopausal women in the USA..... [Detail]
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