The Present Inventors Have Discovered That Threonine Synthase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of Threonine Synthase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, Threonine Synthase Can Be Used As A Target For The Identifica.....
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The Present Inventors Have Discovered That 3-Isopropylmalate Dehydratase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of 3-Isopropylmalate Dehydratase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, 3-Isopropylmalate Dehydratase Can Be Us.....
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The Present Inventors Have Discovered That Asparagine Synthase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of Asparagine Synthase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, Asparagine Synthase Can Be Used As A Target For The Identif.....
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The Present Inventors Have Discovered That Alpha-Aminoadipate Reductase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of Alpha-Aminoadipate Reductase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, Alpha-Aminoadipate Reductase Can Be Used .....
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Neutrophil elastase (NE) is a protease secreted by neutrophils during inflammation. Aberrant expression of NE such as in chronic respiratory inflammatory diseases, results in tissue destruction and decline in lung function. Compositions including an NE-targeting agent that targets the pathologic ele.....
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