Nanoparticle Assembled Hollow Spheres

The new UC technology provides the following benefits:   Simple and easy to prepare ("one-pot synthesis"); General method to produce organic-inorganic hybrid materials; Achieves different structures of hybrid materials that have desirable encapsulation properties; Organics from hybrid spheres can be removed easily to produce hollow spheres; Operates at low temperatures. Nanoparticle Self-Assembly of Hierarchically Ordered Microcapsule Structures "    R. K. Rana, V. S. Murthy, J. Yu, M. S. Wong,    Advanced Materials 2005

This new UC invention has several applications in "nanocapsule" technology, such as:   Drug delivery; Chemical storage and contaminated waste removal; Gene therapy; catalysis; cosmetics; magnetic contrast agents (for use in magnetic resonance imaging) and magnetooptoelectronics.

Scientists at the University of California have developed a novel approach in which nanoparticles can arrange to form hollow sphere and other complex microstructures using particular block copolypeptides as the structure-directing agent. This improved method eliminates hydrolysis and condensation reactions that occur when producing hollow spheres from tetraethylorthosilicate (TEOS) while focusing on the directed assembly properties of these block copolypeptides.

Patent Number: US7563457B2
Application Number: US2002263271A
Inventor: Cha, Jennifer | Deming, Timothy J. | Stucky, Galen D. | Wong, Michael | Birkedal, Henrik | Bartl, Michael H. | Sumerel, Jan L.
Priority Date: 2 Oct 2001
Priority Number: US7563457B2
Application Date: 2 Oct 2002
Publication Date: 21 Jul 2009
IPC Current: A61K000916 | A61K004748 | A61K004800 | C12Q000168
US Class: 424491 | 424489 | 428402 | 977705
Assignee Applicant: The Regents of the University of California
Title: Nanoparticle assembled hollow spheres
Usefulness: Nanoparticle assembled hollow spheres
Summary: Used for medical applications such as delivery of drug molecules, therapeutic compounds, radioactive compounds, chemotherapy agent proteins, deoxyribonucleic acids, ribonucleic acids, magnetic resonance imaging contrast agents, for catalysis, ceramics such as coatings as a thin film of hollow spheres or dielectric material for electronics, as a component in dispersions such as paints, suntan lotions and perfumes, for agricultural applications, for consumer food products, cosmetics and for microparticle containing microdevices for therapeutic agent delivery, sensing and medical imaging.
Novelty: Nanoparticle containing microsphere used for e.g. medical applications such as drug delivery, comprises inner layer having nanoparticle bound to part of structure directing agent, and outer layer coating inner layer

Chemical/Material

Nano Materials

7563457

Related Materials

Additional Technologies by these Inventors

• Initiators For Block-Copolypeptide Synthesis
• Inorganic Coploymer-Dye Composites and Dye-Doped Mesoporous Materials
• Tough, Self-Healing Silicone Materials
• Hierarchically Ordered Porous Oxides
• Hemostatic and Wound Healing Compositions
• High Performance Polymeric Material for Holographic Data Storage
• Supercapacitors for Rechargeable Batteries with Longer Lifetimes (2012-657)
• Hybrid Supercapacitor and Battery System
• UCLA Inventors Create Platform Technology to Create Customizable Nanoscale Particles and Gels for Use in the Industrial Biomaterials Market
• UCLA Inventors Create Platform Technology to Create Customizable Nanoscale Wound Management Tools
• Oxides for Wound Healing and Body Repair
• Hemostatic Compositions And Methods Of Use
• Functionalized Polypeptides by Alkylation of Thioether Groups via Ring Opening Reactions
• Preparation Of Functional Homocysteine Residues In Polypeptides And Peptides
• Compositions Of Polyion Complex Polypeptide Hydrogels

Tech ID/UC Case

10247/2002-069-0

Related Cases

2002-069-0

USA

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