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Nanoparticle Assembled Hollow Spheres

技術優勢: The new UC technology provides the following benefits: Simple and easy to prepare ("one-pot synthesis"); General method to produce organic-inorganic hybrid materials; Achieves different structures of hybrid materials that have desirable encapsulation properties; Organics from hybrid spheres can be removed easily to produce hollow spheres; Operates at low temperatures. Nanoparticle Self-Assembly of Hierarchically Ordered Microcapsule Structures " R. K. Rana, V. S. Murthy, J. Yu, M. S. Wong, Advanced Materials 2005

技術應用: This new UC invention has several applications in "nanocapsule" technology, such as: Drug delivery; Chemical storage and contaminated waste removal; Gene therapy; catalysis; cosmetics; magnetic contrast agents (for use in magnetic resonance imaging) and magnetooptoelectronics.

詳細技術說明: Scientists at the University of California have developed a novel approach in which nanoparticles can arrange to form hollow sphere and other complex microstructures using particular block copolypeptides as the structure-directing agent. This improved method eliminates hydrolysis and condensation reactions that occur when producing hollow spheres from tetraethylorthosilicate (TEOS) while focusing on the directed assembly properties of these block copolypeptides.

*Abstract: Nanoparticles with very small diameters (<100 nm) can be produced from a variety of compositions, such as metals, metal oxides, metal non-oxides, and polymers. The physical, chemical, and electronic properties of nanoparticles differ from those of bulk materials and molecules, which makes them desirable for preparing macroscopic, functional materials and devices. Directed nanoparticle assembly requires highly specific interactions between nanoparticles and organic molecules to achieve controlled construction of the multidimensional nanostructures. Due to their encapsulation properties, hollow spheres provide an attractive structure for many applications. However, current preparation methods are labor-intensive and require multiple, sequential steps.

*Principal Investigation: Name: Michael Bartl
Department:

Name: Henrik Birkedal
Department:

Name: Jennifer Cha
Department:

Name: Timothy Deming
Department:

Name: Galen Stucky
Department:

Name: Jan Sumerel
Department:

Name: Michael Wong
Department:

附加資料: Patent Number: US7563457B2
Application Number: US2002263271A
Inventor: Cha, Jennifer | Deming, Timothy J. | Stucky, Galen D. | Wong, Michael | Birkedal, Henrik | Bartl, Michael H. | Sumerel, Jan L.
Priority Date: 2 Oct 2001
Priority Number: US7563457B2
Application Date: 2 Oct 2002
Publication Date: 21 Jul 2009
IPC Current: A61K000916 | A61K004748 | A61K004800 | C12Q000168
US Class: 424491 | 424489 | 428402 | 977705
Assignee Applicant: The Regents of the University of California
Title: Nanoparticle assembled hollow spheres
Usefulness: Nanoparticle assembled hollow spheres
Summary: Used for medical applications such as delivery of drug molecules, therapeutic compounds, radioactive compounds, chemotherapy agent proteins, deoxyribonucleic acids, ribonucleic acids, magnetic resonance imaging contrast agents, for catalysis, ceramics such as coatings as a thin film of hollow spheres or dielectric material for electronics, as a component in dispersions such as paints, suntan lotions and perfumes, for agricultural applications, for consumer food products, cosmetics and for microparticle containing microdevices for therapeutic agent delivery, sensing and medical imaging.
Novelty: Nanoparticle containing microsphere used for e.g. medical applications such as drug delivery, comprises inner layer having nanoparticle bound to part of structure directing agent, and outer layer coating inner layer

其他

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Tech ID/UC Case

10247/2002-069-0

Related Cases

2002-069-0

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