Chip-Based Droplet Sorting
The invention may be used for monitoring bio-threat agents that contain nucleic acid signatures; biomedical applications (e.g., monitoring infectious diseases and DNA detection); high throughput genetic screening for drug discovery and novel therapeutics; genetic screening for oncology, disease, and personal genomics; forensic purposes; and other research applications (including but not limited to compound discovery, proteomics, and crystallography).
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Patent Number: US20120196288A1
Application Number: US13014792A
Inventor: Beer, Neil Reginald
Priority Date: 27 Jan 2011
Priority Number: US20120196288A1
Application Date: 27 Jan 2011
Publication Date: 2 Aug 2012
IPC Current: C12Q000168 | C12M000134 | G01N003300
US Class: 43500612 | 4220681 | 4350061 | 4352872
Assignee Applicant: Lawrence Livermore National Security LLC,Livermore
Title: Chip-Based Droplet Sorting
Usefulness: Chip-Based Droplet Sorting
Summary: The apparatus is useful for sorting droplets on chip, where the droplets are monodisperse water-in-oil emulsion droplets, used for identifying, monitoring and detecting bio-threat agents that contain nucleic acid signatures, such as spores, bacteria and virus which causes infectious diseases. The apparatus is also useful for detecting host and viral DNA or RNA in biological fluids for forensic purpose and for screening therapeutic drugs.
Novelty: Apparatus useful for sorting droplets on chip for detecting e.g. viral RNA in sample, comprises main flow channel, carrier fluid in main flow channel, droplet maker, analyzer, waste channel and droplet sorter
Biomedical
DNA/Gene Engineering
Tech ID/UC Case 22545/2011-668-0 Related Cases 2011-668-0
USA
