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Parathyroid hormone derivative for treatment of osteoporosis
Summary
Hesham Tawfeek, M.D.
Technology Benefits
Effectively increases bone mass in mice.Does not induce osteoclast formation in cell culture.Weaker extra-skeletal side effects than PTH (1-34).Smaller peptide is easier to synthesize.Patent information:Patent Pending Tech Ventures Reference: IR CU13330
Technology Application
Treatment for diseases in which bone formation is beneficial, such as osteoporosis.Cell culture methods to detect osteoclast formation can be used to study osteoclasts Could be developed for drug screens to identify bone anabolic peptides without osteoclast formation.Could also be modified to prolong duration of action and decrease frequency and change route of administration.
Detailed Technology Description
Hesham Tawfeek, M.D.
Country/Region
USA
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