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Nkx3.1/Pten Mutant Mouse Cell Line for the Study of Prostate Carcinogenesis

Technology Benefits
This cell line provides a model system for the study of key features of human prostate adenocarcinomas
Technology Application
The study of prostate carcinogenesisCharacterization of prostate adenocarcinomasDevelopment of potential treatments for prostate cancer
Detailed Technology Description
Nkx3.1 homeobox gene has restricted expression in the prostate and essential roles in prostate differentiation and function. PTEN represents a frequent target of mutational inactivation in human cancers, and Pten heterozygous mutant mice develop canc...
*Abstract
None
*Inquiry
Peter GolikovColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu
*IR
2305
*Principal Investigator
*Publications
Abate-Shen, C et al. (2003) Cancer Res. 63:3886-90.
Country/Region
USA

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