Nkx3.1/Pten Mutant Mouse Cell Line for the Study of Prostate Carcinogenesis
- 技术优势
- This cell line provides a model system for the study of key features of human prostate adenocarcinomas
- 技术应用
- The study of prostate carcinogenesisCharacterization of prostate adenocarcinomasDevelopment of potential treatments for prostate cancer
- 详细技术说明
- Nkx3.1 homeobox gene has restricted expression in the prostate and essential roles in prostate differentiation and function. PTEN represents a frequent target of mutational inactivation in human cancers, and Pten heterozygous mutant mice develop canc...
- *Abstract
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None
- *Inquiry
- Peter GolikovColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu
- *IR
- 2305
- *Principal Investigation
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- *Publications
- Abate-Shen, C et al. (2003) Cancer Res. 63:3886-90.
- 国家/地区
- 美国
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