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Injectable Elastic Polymeric System for Controlled Drug Delivery

Summary

Researchers at Purdue University have developed a functionalized hyaluronic acid (HA), a thermo-responsive elastic polymer system comprising functionalized HA, and the methods of fabrication and utilization for drug delivery. This polymer system is injectable and may be used for spatio-temporally controlled delivery of analgesics, anesthetics, antibodies, and other drugs as well as growth factors. Controlled drug delivery offers numerous advantages when compared to conventional dosage forms including improved efficacy, reduced toxicity, reduced need for specialized drug administration, and improved patient compliance/convenience. In addition, HA offers numerous useful biological benefits including wound healing, cell adhesion and proliferation, cell motility, angiogenesis, cellular signaling, and matrix organization.

Technology Benefits

Injectable Thermo-responsive Highly elastic Controlled drug delivery

Technology Application

Medical/Health Drug delivery Tissue engineering

Detailed Technology Description

Meng DengDeng LabPurdue Agricultural & Biological EngineeringPurdue Biomedical EngineeringPurdue Materials Engineering

Countries

United States

Application No.

None

*Abstract

*Background

Medications are drugs used to treat, cure, prevent, or diagnose an illness or medical condition. However, sometimes drugs are not effective by simply being ingested. Delivery of local or systemic drugs requires targeted doses to specific parts of the body. The accuracy of delivery is often hampered by inferior mechanical performance of the material used for delivery.

*IP Issue Date

None

*IP Type

Provisional

*Stage of Development

Process validation in lab

*Web Links

Purdue Office of Technology CommercializationPurdue Innovation and EntrepreneurshipMeng DengDeng LabPurdue Agricultural & Biological EngineeringPurdue Biomedical EngineeringPurdue Materials Engineering

Country/Region

USA