Injectable Elastic Polymeric System for Controlled Drug Delivery
Researchers at Purdue University have developed a functionalized hyaluronic acid (HA), a thermo-responsive elastic polymer system comprising functionalized HA, and the methods of fabrication and utilization for drug delivery. This polymer system is injectable and may be used for spatio-temporally controlled delivery of analgesics, anesthetics, antibodies, and other drugs as well as growth factors. Controlled drug delivery offers numerous advantages when compared to conventional dosage forms including improved efficacy, reduced toxicity, reduced need for specialized drug administration, and improved patient compliance/convenience. In addition, HA offers numerous useful biological benefits including wound healing, cell adhesion and proliferation, cell motility, angiogenesis, cellular signaling, and matrix organization.
Injectable Thermo-responsive Highly elastic Controlled drug delivery
Medical/Health Drug delivery Tissue engineering
Meng DengDeng LabPurdue Agricultural & Biological EngineeringPurdue Biomedical EngineeringPurdue Materials Engineering
United States
None
美国
