A low-cost perfusion bioreactor for tissue-engineered tubular constructs
- Detailed Technology Description
- None
- *Abstract
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The inventors have developed a novel system to perfuse tissue-engineered tubular grafts (TETGs). The system consists of a cost-effective bioreactor that was designed in order to homogeneously perfuse tubular constructs by creating a continuous flow of media into their lumen. In the initial phase, the flow of the culture is dynamic without generating the forces of shear stress which minimizes cell loss.Application* Any tissue engineering application involving 3D tubular contstructs such as blood vessels, urethra, nerves, airways, bowels, etc. Advantages* Simple* Cost-effective* Minimal maintanance* Minimal user interaction* Fluid dynamically efficientAvailable as a research tool
- *Principal Investigator
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Name: Lorenzo Soletti, Student
Department: Med-Surgery
Name: David Vorp, Assistant Professor
Department: Engr-Dept Chairperson's Office
- Country/Region
- USA
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