Synthetic Peptide Targeting Critical Sites On The Sars-Associated Coronavirus Spike Protein Responsible For Viral Infection And Method Of Use Thereof
- Summary
- The Present Invention Provides Methods For Locating Critical Portions Or Sites On The Spike Protein (S Protein) Of Sars-Associated Coronavirus (Sars-Cov) Responsible For The Viral Infection That Causes Severe Acute Respiratory Syndrome (Sars). The Present Invention Also Provides New Synthetic Peptides Targeting Such Critical Portions Or Sites Of The S Protein Of Sars-Cov For Preventing Or Treating Of Sars-Cov Infection In A Subject. The Present Invention Further Provides Methods Of Testing Antiviral Activity Exerted By Antiviral Agents Using Real-Time Quantitative Pcr.
- Supplementary Information
- Patent Number: US7491489B2
Application Number: US2005262044A
Inventor: Zheng, Bojian | Guan, Yi | Huang, Jiandong | He, Ming-Liang
Priority Date: 22 Nov 2004
Priority Number: US7491489B2
Application Date: 28 Oct 2005
Publication Date: 17 Feb 2009
IPC Current: C12Q000100 | C12Q000118 | C12Q000170 | G01N003353
US Class: 435004 | 435005 | 4350071 | 43500721
Assignee Applicant: The University of Hong Kong
Title: Synthetic peptide targeting critical sites on the SARS-associated coronavirus spike protein responsible for viral infection and method of use thereof
Usefulness: Synthetic peptide targeting critical sites on the SARS-associated coronavirus spike protein responsible for viral infection and method of use thereof
Summary: (M1) is useful for locating portions of SARS-CoV S protein responsible for causing viral infection in a cell, where the cell is from a primate or human. (M2) is useful for preventing or inhibiting SARS-CoV infection in a subject, where the subject is a cat, horse, sheep, pig, dog, cat, rodent, chicken or primate, or human being. (All claimed).
- Industry
- Biomedical
- Sub Category
- Pathogen
- Application No.
- US2005262044A
- Country/Region
- Hong Kong
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