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Bioactive And Osteoprorotic Bone Cement

Summary

A Composition For Use As A Bioactive Bone Cement Having A Powder Component Including Strontium-Containing Hydroxy Apatite And Formulated To Create A Settable Fluid Substance When Mixed With A Liquid Component. The Liquid Component Includes A Bisphenol A Diglycidylether Dimethacrylate Resin Which When Mixed With The Powder Component Creates A Bioactive Bone Cement. The Bioactive Bone Cement Can Alternatively Be In The Form Of A Two Paste Component System In Which A First Paste Component Including Strontium-Containing Hydroxy Apatite, Bisphenol A Diglycidylether Dimethacrylate Resin And A Polymerization Initiator Is Formulated To Create A Settable Paste Substance When Mixed With A Second Paste Component.; The Second Paste Component Includes Strontium-Containing Hydroxy Apatite, Bisphenol A Diglycidylether Dimethacrylate Resin, And A Polymerization Accelerator Which When Mixed Together With The First Paste Component Creates A Bioactive Bone Cement.

Supplementary Information

Inventor: LI Y | WEIJIA W L | MAN C K C
Priority Number: CN1229146C
IPC Current: A61L002700 | A61K0006033 | A61K0006083 | A61L002400
Assignee Applicant: Gangda Hengde Bone Biocology Sci & Techn
Title: Bioactive and osteoprorotic bone cement | Is provided with biological activity and treating osteoporosis
Usefulness: Bioactive and osteoprorotic bone cement | Is provided with biological activity and treating osteoporosis
Summary: The bone cement compositions are used to bond or fix implant materials,to strengthen damaged natural bone or (claimed) acts as a carrier for osteoinductive drugs and have their own chemical effects on improving osteoporosis. They are used to treat spinal fractures, to augment long or flat bone fractures and stabilize their fractured fragments, and to improve bone strength in osteoporotic bones. They are used to augment bone-screw or -implant interfaces and to carry and deliver drugs including antibiotics, bone-inducing agents, cytotoxic agents and cells (e.g. cells used for gene therapy and cells normally found in the bone marrow) to bone. They are used as bone fillers in areas of the skeleton where bone may be deficient e.g. post-trauma with segmental bone loss, post-bone tumor surgery where bone has been excised and after total joint arthroplasty. They may be used to hold and fix artificial joint components inpatients undergoing arthroplasty, as a strut to stabilize the anterior column of the spine after excision surgery and as a bone graft substitute in spinal fusions.
Novelty: Bioactive bone cement compositions comprise powder component including strontium-containing hydroxyapatite and liquid component including bisphenol A diglycidylether dimethacrylate resin

Industry

Biomedical

Sub Category

Medical Implant

Country/Region

Hong Kong