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Specific inhibition of caspase-2 activation for the treatment of neurodegenerative diseases


Summary

This technology is a membrane-permeable hexapeptide that specifically inhibits caspase-2 signaling in the central nervous system to treat neurodegenerative diseases.


Technology Benefits

Specifically inhibits caspase-2 signalingDoes not interfere with other cellular pathways in the brainPenetrates cell membranes for enhanced drug delivery


Technology Application

Treatment of neurodegenerative diseases, including Alzheimer’s disease, mild cognitive impairment Parkinson’s disease, Huntington’s chorea, amyotrophic lateral sclerosis, and Creutzfeld-Jacob diseaseResearch tool for understanding the role of caspase-2 and RAIDD in cellular signaling


Detailed Technology Description

None


Country/Region

USA

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