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Peptide Mimotopes to Oxidation Specific Epitopes

Technology Application

In conjunction with different carriers, the newly identified peptides can be used as immunogens to study the mechanistic role of MDA-specific immune responses in immunization studies, and may provide the basis for potential atheroprotective vaccines, and could also be useful as imaging agents for inflammatory sites and/or atherosclerotic lesions.

Detailed Technology Description

UCSD researchers have identified two peptide mimotopes that form a three dimensional representation of critical epitopes of MDA. These mimotopes have been shown to be representative of oxidation-specific epitopes that are proinflammatory and proatherogenic.

Industry

Chemical/Material

Sub Group

Chemical/Material Application

Others

Tech ID/UC Case

22613/2012-183-0

Related Cases

2012-183-0

Country/Region

USA

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