New Anti-Microbial and Anti-Biofilm Silicone Formulation
The new silicone formulation may be useful for urinary tract stents, catheters, and nephrostomy tubes. In addition, it may possibly be of value in the development of a prosthetic bladder material for partial or eventually even total replacement of the bladder.
Scientists and physicians at the University of California, Irvine have developed a new silicone formulation that appears to be resistant to encrustation and biofilm formation during in vitro testing. Further in vivo studies are in progress.
Patent Number: US8257827B1
Application Number: US13151704A
Inventor: Shi, Frank | Clayman, Ralph | Louie, Michael K. | Lin, Yeong-Her | Lin, Yuan-Chang
Priority Date: 2 Jun 2011
Priority Number: US8257827B1
Application Date: 2 Jun 2011
Publication Date: 4 Sep 2012
IPC Current: B32B000516
US Class: 428328 | 524403
Assignee Applicant: The Regents of the University of California
Title: Silicone composition and devices incorporating same
Usefulness: Silicone composition and devices incorporating same
Summary: The method is useful for forming silicone having anti-microbial properties (claimed) which is useful in medical devices e.g. catheters, diaphragms, seals in dialysis equipment, brain surgery-related products, cosmetic and repair parts, heart surgery-related products, medical tubing, ureteral stents, urinary bladder catheters, nephrostomy tubes and an artificial urinary bladder/reservoir.
Novelty: Forming silicone having anti-microbial properties, used in medical devices e.g. catheters, comprises e.g. adding silica and nanoparticles to liquid vinyl-terminated polydimethylsiloxane and adding coupling agent to above mixture and heating
Chemical/Material
Chemical/Material Application
8257827
Tech ID/UC Case 18707/2009-147-0 Related Cases 2009-147-0
USA
