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PISA (Pyhin Protein Stimulating ASC) Triggers Inflammasome Activation in Response to Cytosolic B-DNA
Detailed Technology Description
This patented invention discloses methods for identification and compounds found to modulate the PISA receptor and it's downstream immune response. The innate immune system recognizes non-self genetic material and mounts a defensive immune response. However, self cytosolic DNA at times gets targeted and the process by which this phenomenon occurs
Countries
Not Available
Application No.
None
Country/Region
USA
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