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Sensitive Folate Receptor Detection by Immunomagnetic Diffractometry

Summary

Researchers at Purdue University have developed an integrated approach for the rapid detection of the folate receptor (FR) using in situ assembled optical diffraction gratings in combination with immunomagnetic capture. With this approach, a detection sensitivity of 700 fM (20 pg/ml) was achieved without any fluorescent or radiolabels or any secondary signal amplification. This approach can be applied to other targets and has the potential to be a broadly applicable, highly sensitive analysis technique.

Technology Benefits

Allows early detection of cancerSensitive to femtomolar concentrations Simpler assay with lower detection limit compared to current standard

Technology Application

Cancer DetectionMedical/Healthcare

Detailed Technology Description

Cagri SavranSavran Research GroupPurdue Mechanical Engineering

Countries

United States

Application No.

None

Country/Region

USA

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