Releasable Magnetic Cell Capture System

The system:ΓÇóIs multifunctional, comprising target specific magnetic nanoparticlesΓÇóEnables an effective control of particle size, ranging from 600-800 nmΓÇóIs highly simple, specific, versatile and cost effective as compared to conventional techniquesΓÇóAllows for a rapid detection as compared to the existing techniquesΓÇóIs capable of capturing few hundred cells/ml of blood sample, with possibility of further lowering the detection limitΓÇóAllows for an efficient release of captured particles using a competitive binding based approachΓÇóCompletely avoids alteration of cellular behavior of the captured cells as compared to conventional systemsΓÇóEffectively capture and purify cells in vitro from blood, plasma, saliva and other body fluidsΓÇóWould be commercially useful for the following applications:o Disease diagnostics and monitoringo Separation and purification of cancer cells such as thyroid, lung, breast, pancreas, and ovaryo Separation of intracellular parasite infection, infectious pathogens and microorganisms from body fluids, tissue samples, food and watero Capturing and separation of rare molecular markers for human and/or animal diseaseso Understanding physiological, biochemical and genetic profile of less understood systems such as circulating tumor cells

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USA