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Probiotic Supplement for Delaying or Preventing the Onset of Type 1 Diabetes

IP Title: Lactobacillus Supplement for Alleviating Type I Diabetes

Detailed Technology Description: None

Application Date: Jul 11, 2011

Application No.: 9,474,773

Others: Lead PI Neu Pivot info
http://pivot.cos.com/profiles/992367C8CE47B01E00178DAF57E34853?h=lastname:Neu

*Abstract

Alleviates Type 1 Diabetes by Utilizing Probiotic Compositions as Food Additives

This Lactobacillus supplement prevents Type 1 diabetes by preventing the onset of autoimmunity that leads to Type 1 diabetes. Type 1 diabetes represents approximately five to ten percent of all human diabetes and the Centers for Disease Control and Prevention estimate that between 500,000 to one million Americans are living with the disease. According to the Food and Agricultural Organization, probiotics are live microorganisms which, when administered in adequate amounts, confer a health benefit on the host. In recent years, much interest has been shown in the use of the lactic acid bacteria Lactobacilli as probiotic organisms and their potential for disease prevention in both humans and animals. Researchers at the University of Florida have developed unique probiotic compositions for alleviating Type 1 diabetes comprised of an effective amount of one or more Lactobacillus isolates.

Application

Probiotic compositions as food additives that are useful in preventing or delaying the development of Type 1 diabetes

Advantages

Lactobacillus compositions can delay or prevent the onset of autoimmunity that leads to type 1 diabetes
Modifies the gut microbiota and decrease oxidative stress and inflammation, reducing intestinal leakage
Could potentially reduce the rate of Type 1 diabetes development and thereby reduce healthcare costs

Technology

Type 1 diabetes, also known as immune-mediated, juvenile, or insulin-dependent diabetes mellitus, is a disease of children and adults for which there is no adequate means for prevention or cure. Lactic acid bacteria and bifidobacteria are the most common types of microbes used as probiotics and have emerged as two dominant groups negatively correlated with the onset of type 1 diabetes. University of Florida researchers have developed probiotic compositions consisting of Lactobacillus isolates that can be used as food additives (probiotics) to prevent or slow the development of type 1 diabetes.

*IP Issue Date: Oct 25, 2016

*IP Publication Date: Jul 19, 2012

*Principal Investigator: Name: Josef Neu
Department:

Name: Desmond Schatz
Department:

Name: Eric Triplett
Department:

Name: Graciela Lorca
Department:

Name: Mark Atkinson
Department:

Country/Region: USA

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