Lock-in Free Stimulated Raman Microscope
- Summary
- Purdue University researchers have developed a small, robust component that eliminates the lock-in amplifier currently required for stimulated Raman imaging, thereby improving the signal to noise ratio by one order of magnitude over the current lock-in based detection. By eliminating the need for the lock-in amplifier, this technology will allow high-speed stimulated Raman imaging in a simple way by non-experts.
- Technology Benefits
- Improved signal to noise ratio over the current lock-in based detectionIncreased detection sensitivity
- Technology Application
- Chemical Imaging
- Detailed Technology Description
- Ji-Xin ChengCheng LaboratoryPurdue Biomedical EngineeringPurdue Chemistry
- Countries
- United States
- Application No.
- None
- *Abstract
-
- *Background
- Chemical imaging is the simultaneous measurement of chemical and spatial information in order to generate a visual image of the distribution of the components of a molecule. Raman imaging is a technique used to study the vibration and rotation of the molecule. Currently, stimulated Raman imaging requires a lock-in amplifier; however, the lock-in amplifier's electronic noise limits detection sensitivity.
- *IP Issue Date
- None
- *IP Type
- Other Patent
- *Stage of Development
- Process Validation in Lab
- *Web Links
- Purdue Office of Technology CommercializationPurdueInnovation and EntrepreneurshipJi-Xin ChengCheng LaboratoryPurdue Biomedical EngineeringPurdue Chemistry
- Country/Region
- USA
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