Lead Inventors: Faye (Nina) P. Wacholder, PhD Problem or Unmet Need:Statistical techniques for identifying keywords in a document traditionally rely on calculating the frequency of individual stems and/or words. However, stems are ambiguous ("trad" might refer to "trader" or "tradition"), as are the.....
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Studying protein-protein interactions in living cells reveals critical information about cell signaling dynamics and cellular mechanisms in both normal and disease conditions. Genetically-encoded fluorescent reporters are ideal for these purposes because they allow non-invasive imaging. However, man.....
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Our scientists have identified a protein‐protein coupling between the glutamate R2 (GluR2) ‐ α‐amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionic acid (AMPA) receptor and the extracellular protein glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) as a novel target for the treatment of the neurodegenerativ.....
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