This invention relates to the production of dual models of Congenital Heart Defects and Hypertrophic Cardiomyopathy with the use of mice which are genetically modified by transgenic (gene-knockout) techniques. The present invention produces knockout mice that show multiple cardiovascular malformatio.....
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PROBLEM TO BE SOLVED: To provide a technique for screening and detection of a cystic fibrosis(CF) carrier, CF diagnosis and therapy. SOLUTION: The CF protein gene usable for screening and detection of the carrier, CF diagnosis and therapy is cloned, isolated and purified.
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The present invention provides an oral DNA composition for improving an impaired immunity associated with chronic infection of hepatitis B virus (HBV) comprising an attenuated strain of bacterial cells which preferentially target phagocytic cells of the intestin al mucosa, and which serve as a vehic.....
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A general, efficient, and environmentally friendly method is provided for producing mostly beta-epoxides of DELTA5-unsaturated steroids using certain ketones as the catalyst along with an oxidizing agent, or by using certain dioxiranes. In another aspect of the invention, a method is provided for pr.....
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Bacterial lipopolysaccharide (LPS) in systemic circulation triggers deleterious super-inflammatory response, which is key pathogenesis of many disorders like gram-negative sepsis and necrotizing enterocolitis. No effective therapeutic interventions are currently available for protection of patients .....
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