ANTI-INFLUENZA COMPOUNDS
- Summary
- The present invention provides pyrimidinyl compounds of formula (I) and pharmaceutically acceptable salts thereof. These compounds may be used for the inhibition of influenza. In particular, the compounds of the invention may be used for the treatment or prophylaxis of influenza A, most particularly H1N1 or H5N1 influenza. The compounds of the invention can also be used for the treatment or prophylaxis of a disease caused by Vibrio cholerae, Clostridium perfringens, Streptococcus pneumoniae, Arthrobacter sialophilus, an orthomyxovirus, a paramyxovirus, a parainfluenza virus, mumps virus, Newcastle disease virus, fowl plague virus or Sendai virus.
- Supplementary Information
- Patent Number: US8673884B2
Application Number: US2010866118A
Inventor: Jones, Steven J. | Lau, Allan Sik-Yin | An, Jianghong | Law, Hing Yee | Lee, Chun Wai Davy | Poon, Lit Man
Priority Date: 5 Feb 2008
Priority Number: US8673884B2
Application Date: 4 Aug 2010
Publication Date: 18 Mar 2014
IPC Current: C07D023946 | A61K003113 | A61K0031215
US Class: 514086 | 514272 | 544243 | 544321
Assignee Applicant: Versitech Limited | British Columbia Cancer Agency Branchncouver, British Columbia
Title: Anti-influenza compounds
Usefulness: Anti-influenza compounds
Summary: In pharmaceutical composition useful for treatment or prophylaxis of influenza (selected from influenza type A, B or C (preferably type A group-1 or type A group-2), H1N1, H1N2, H3N2, H5N1, H9N2, H7N3, H7N7, type A H5N1 or type A H1N1); drug-resistant strain of influenza; disease caused by Vibrio cholerae , Clostridium perfringens , Streptococcus pneumoniae , Arthrobacter sialophilus , orthomyxovirus, paramyxovirus, parainfluenza virus, mumps virus, Newcastle disease virus, fowl plague virus or Sendai virus; and inhibition of endogenous mammalian sialidases (claimed).
Novelty: New pyrimidinyl compounds useful for treatment or prophylaxis of influenza, e.g. type A H5N1 influenza, type A H1N1 influenza, and disease caused by, such as Vibrio cholerae, orthomyxovirus
- Industry
- Biomedical
- Sub Category
- Pathogen
- Application No.
- US2010866118A
- Country/Region
- Hong Kong
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