Shih-Fu Chang, Ph.D.
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This technology describes a method for treating ID2 protein-related diseases through increased degradation of Hypoxia-Inducible Factors (HIFs).
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Inventor: Emil RacilaDepartment of Pathology
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Inventor: Sarah C. LarsenAssociate Professor, Department of ChemistryAssociate Director of Nanoscience and Nanotechnology Institutehttp://ccs14.chem.uiowa.edu/faculty/larsen/group/group.html
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Description: This technology uses RNAi to reduce target mRNA to treat diseases in the pulmonary airway such as asthma, COPD, and Cystic Fibrosis. This has been shown to work in well-differentiated airway epithelial cells. The method involves contacting the cell with a sensitizing agent followed by c.....
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