A novel process for synthesizing multiple Topoisomerase I inhibitors that have optimized structures for the greatest inhibitory activity and cytoxicity towards dividing cells was developed.
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This technology from the laboratory of Dr. Rigoberto Advincula at Case Western Reserve University provides for hydrogel coating that is attached to a proppant substrate in a core-shell structure to en
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UCLA researchers have developed knockout mice in which the Synaptotagmin 4 (Syt4) gene is deleted. Synaptotagmin 4 is involved in a number of neurobiological events, including vesicle fusion and neurotransmitter release at neuronal synapses. These mice can be used to study many central nervous syste.....
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This invention describes a synthetically engineered immune organoid for growth, proliferation, activation,differentiation, and immunoglobulin switching of primary naïve B cells in a threedimensional structure.
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