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Synaptotagmin-4 Knockout Mice

Detailed Technology Description

UCLA researchers have developed knockout mice in which the Synaptotagmin 4 (Syt4) gene is deleted. Synaptotagmin 4 is involved in a number of neurobiological events, including vesicle fusion and neurotransmitter release at neuronal synapses. These mice can be used to study many central nervous system (CNS) functions, including memory, learning, fear and anxiety

Others

Related Materials

Ferguson GD, et al. Deficits in memory and motor performance in synaptotagmin IV mutant mice. Proc Natl Acad Sci U S A. 2000 May 9;97(10):5598-603.
Additional information on Mouse Strain #012400 from The Jackson Laboratory.

Additional Technologies by these Inventors

Tech ID/UC Case

21497/2010-498-0

Related Cases

2010-498-0

Country/Region

USA

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