Neutrophil elastase (NE) is a protease secreted by neutrophils during inflammation. Aberrant expression of NE such as in chronic respiratory inflammatory diseases, results in tissue destruction and decline in lung function. Compositions including an NE-targeting agent that targets the pathologic ele.....
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Methods For Treating Or Preventing One Or More Symptoms Of Rheumatoid Arthritis Or Other Types Of Inflammatory Arthritis Involves Administering A Formulation Containing An Effective Amount Of Arsenic Trioxide To An Affected Patient. The Arsenic Trioxide Formulation Can Be Administered Orally, For Ex.....
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The expression or methylation of tumor suppressor genes is used as biomarkers for the diagnosis and prognosis of gastric and colon cancer, and methods for inhibiting the growth of gastric and colon cancer. Highlights: • Tumor suppressor genes in gastric cancer (ZNF545, ADAMTS9, DACT1, RNF180, BCL.....
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The Present Inventors Have Discovered That Alpha-Aminoadipate Reductase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of Alpha-Aminoadipate Reductase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, Alpha-Aminoadipate Reductase Can Be Used .....
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The Present Inventors Have Discovered That 3-Isopropylmalate Dehydratase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of 3-Isopropylmalate Dehydratase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, 3-Isopropylmalate Dehydratase Can Be Us.....
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