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GFP-Amplification Mutagenesis Assay (GMA): Quantitative, Scalable Detection of Chemical Mutagenesis

Preserves the exquisite specificity of the Ames testQuantitative readout dramatically decreases the amount of sample and of reagents necessary to carry out the testSignificant cost-savings for compounds in early stages of development [更多]

Tags: drug development Other Cancer antimicrobial Screening Assays screening drug discovery genomics Health Bioinformatics molecular biology high throughput screening Quality Control high throughput Mutagenesis Ames test directed evolution early detection genotoxicity antitumor Carcinogenesis mutagenesis reversion assay random mutagenesis point mutations frameshifts Cat2

Glycine alpha1 KK385 knockin mice

None [更多]

Tags: transgenic mouse alcoholism treatment

Glycoconjugates of Antiproliferative Iron Pro-Chelators Targeting Cancer Cell Metabolism

Technology ID: UA15-085 Technology Background: Cancer cells require higher iron levels in order to sustain fast proliferation rates, and have high glucose demands to sustain growth. This vulnerability of malignant behavior can be targeted by the use of small-molecule chelators that interfere with th..... [更多]

Tags: none

Gold Catalyzed Hydroamination of Alkynes and Allenes

Hydroamination of alkynes and allenes Production of pharmaceuticals/bioactive molecules [更多]