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Lead Inventors: Eric Kandel, Ph.D.Problem or Unmet Need:Ion channels, a group of specialized proteins in the membranes of nerve and muscle cells, play essential roles in the physiology of all cells. In recent years ion channels have been implicated in a long list of diseases, including cystic fibros..... [更多]
The present device and method can be used to monitor therapeutic treatment of methemoglobinemia using methylene blue. Also, the device and method can be used for cyanide toxicity treatment with therapeutically induced methemoglobin and in neonatal methemoglobinema management during inhaled nitric ox..... [更多]
Neurodegenerative diseases, such as Parkinson’s, Alzheimer’s, and Huntington’s, are characterized by misfolded proteins that aggregate and induce neuronal toxicity and death. Protein disulfide isomerase (PDI) is an enzyme implicated in protein misfolding and has been shown to be upregulated in the b..... [更多]
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