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Background:Glaucoma is a disease characterized by intra-ocular pressure sufficient to damage the optic nerve and cause permanent impairment of vision. Glaucoma is rarely cured, but its progression can be greatly delayed by reducing the intra-ocular pressure with medicines, laser procedure or surgery..... [更多]
The study of social behavior in groups of mice may have crucial implications for understanding the social aspects of different disorders. To be executed correctly, group studies require the ability to track individual’s behavior within the group structure. The main challenge of current research too..... [更多]
Alkylating agents are the most widely used anticancer drugs. Drug resistance is a major obstacle in the successful treatment of cancer by alkylating agents. The DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) has been implicated in resistance of human tumors to alkylating agents. ..... [更多]
BBS is a monoclonal antibody that binds specifically and blocks beta-secretase (BACE1) cleavage site on its substrate, APP. BBS inhibits Ab production, a hall-mark of AD and other neurodegenerative diseases such as ALS.The mechanism of action of BBS is based on binding of the antibody at the cell s..... [更多]
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