Interleukin 17 (IL-17) represents a family of pro-inflammatory cytokines consisting of six members, termed IL-17A-F. IL-17A is expressed by a unique lineage of CD4 T cells (Th-17) and is known to stimulate fibroblasts, endothelial cells, epithelial cells and macrophages to produce multiple pro-infla.....
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Additional material on the technology can be supplied upon request
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Female mice are fed with diets rich in specific f.a. (saturated or unsaturated) during pregnancy and/or lactation. The offspring is raised on a regular diet or on a fat rich diet, and develops obesity, fatty liver, and insulin resistance, depending on the diet received in utero. The model allows stu.....
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