ER stress, elicited by chemotherapeutic agents such as doxorubicin, 5FU, vincristine and bortezomib, or statins such simvastatin, triggers cell death at least in part through generation of leukotriene C4 (LTC4), which induces ROS accumulation, DNA damage and subsequent cell death. LTC4 can be produc.....
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LV Track is a decision support system for routine quantitative evaluation of LV function. Our proprietary algorithm enables fast and accurate analysis of echocardiographic cine loops for automatic extraction of LV parameters.• A basic prototype of the system (MATLAB) has been developed.• The system .....
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Infra-red (IR) imaging (in the LWIR and MWIR bands) is widely used for observation and surveillance applications. Most of IR optical materials are very sensitive to temperature changes. This sensitivity is reflected in a temperature dependent refractive index, that in turn it affects the focal lengt.....
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A subchondral defect is usually characterized by a structural breakdown of the articular cartilage and the bone underneath due to trauma or disease, leading to chronic disabilities. Treating such defects is an important medical target since in the adult patient, damaged cartilage cannot spontaneousl.....
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Metal-oxide material generates electromechanical stress an order of magnitude above existing materials.The ability to develop a mechanical stress in response to the application of an external electric field has many uses, and characteristic materials are classified as either piezoelectric or electro.....
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