Immunotherapy, that is the use of the immune system to treat cancer, is currently a leading candidate in the combat against cancer. Unlike the toxic effects of both chemotherapy and radiation, immunotherapy is considered to have mild side effects due to its ability to differentiate between healthy a.....
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ER stress, elicited by chemotherapeutic agents such as doxorubicin, 5FU, vincristine and bortezomib, or statins such simvastatin, triggers cell death at least in part through generation of leukotriene C4 (LTC4), which induces ROS accumulation, DNA damage and subsequent cell death. LTC4 can be produc.....
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Animal eye models for evaluation of systemic and topical use of new medications, devices and delivery systems. The models include external eye, intraocular, orbital, and optic nerve applications.
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A study by Prof. Karin showing that autoantibodies are produced against several key mediators of the destructive process in inflammatory autoimmunity and cancer, has been the bases for his development of these autoantibodies as both diagnostic biomarkers and predictive biomarkers for assessing clini.....
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Unmanned aerial vehicles (UAVs), have limited flight endurance and also limited communications capabilities. Flight duration (or endurance) is presently bounded by the limited available energy storage (fuel or batteries) on the UAVs. Communication speeds are limited by the RF links now on UAVs, havi.....
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