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Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and has become a global health threat. No HCV vaccine is currently available and treatment with antiviral therapy is associated with adverse side effects. Moreover, there is no preventive therapy for recurrent hepatitis C po..... [更多]
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and has become a global health threat. No HCV vaccine is currently available and treatment with antiviral therapy is associated with adverse side effects. Moreover, there is no preventive therapy for recurrent hepatitis C po..... [更多]
Need:Insertion of intravenous (IV) catheter is a common clinical procedure carried out 190 million times per year in the United States alone.While the procedure is common, it is associated with high failure rates:30% failure in Adults44% failure in Children Common causes for failure:Misidentificatio..... [更多]
Need:There is a strong need for novel targeted based approaches for type II diabetes management. Innovation: We propose to develop selective antagonist for novel target to reduce beta-cell damage as a potential treatment for type 2 diabetes. We provide the first evidence of rescuing beta-cell death ..... [更多]
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