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Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and has become a global health threat. No HCV vaccine is currently available and treatment with antiviral therapy is associated with adverse side effects. Moreover, there is no preventive therapy for recurrent hepatitis C po..... [Detail]
Need:There is a strong need for novel targeted based approaches for type II diabetes management. Innovation: We propose to develop selective antagonist for novel target to reduce beta-cell damage as a potential treatment for type 2 diabetes. We provide the first evidence of rescuing beta-cell death ..... [Detail]
Background:The problem is how to match XML query twig patterns in a parallel graphics processing unit (GPU) multi-threaded computing platform. There are sequential solutions to this problem such as the PathStack/TwigStack algorithm and its parallelization for corresponding CPU multi-threaded computi..... [Detail]
Polydopamine (PDA) is a polymer based on the chemical composition of mussel adhesive protein which mediates attachment to wet surfaces. The interfacial adhesive properties of PDA allows introduction of new functionalities, including anti-bacterial activity, even to inert surfaces. Development of a..... [Detail]
Amyotrophic Lateral Sclerosis (ALS) also named Lou Gehrig's disease, is a fatal neurodegenerative disease characterized by the progressive degeneration of cortical brain neurons, brainstem and, upper and lower motor neurons. Within short time, the disease leads to limb paralysis, compromise of speec..... [Detail]
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