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The present device and method can be used to monitor therapeutic treatment of methemoglobinemia using methylene blue. Also, the device and method can be used for cyanide toxicity treatment with therapeutically induced methemoglobin and in neonatal methemoglobinema management during inhaled nitric ox..... [Detail]
Neurodegenerative diseases, such as Parkinson’s, Alzheimer’s, and Huntington’s, are characterized by misfolded proteins that aggregate and induce neuronal toxicity and death. Protein disulfide isomerase (PDI) is an enzyme implicated in protein misfolding and has been shown to be upregulated in the b..... [Detail]
Technology: Researchers at MUSC have identified multiple gene variants that are critical for the response to opioid receptor antagonists, including naltrexone for AUD. First, recent work has further validated that carriers of OPRM1 asp40/ DAT10 variable number tandem repeat (VNTR) and asn40/ DAT9 va..... [Detail]
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