Effectiveagainst Methicillin-resistant Staphylococcus aureus (MRSA)Specificfor bacterial NOS enzymeSynergisticwith other antibiotics
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Lead Inventors: Scott A. Snyder, Ph.DProblem or Unmet Need:Compounds that can potentially delay or reverse the progression of neurodegenerative diseases, such as Huntington's disease, are highly sought after. Natural products offer a vast selection of biologically active starting material for synthe.....
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A series of novel lipid derivatives of phosphonate compounds has been synthesized. These novel compounds have been shown to promote oral uptake and increase delivery of the conjugate to the lung in animal models when compared with the parent compounds. A similar derivatization strategy can also be a.....
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Traditional vaccine approaches have many limitations. For example, killed pathogen vaccines are expensive, require additional adjuvants, multiple doses, and often have undesirable side effects. Live modified or recombinant attenuated bacterial or virus vectored vaccines may revert to virulence. In c.....
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